Nadide Akdeniz was graduated from the Painting–Graphics Department of Gazi Education Institute in 1966, where she studied under Turan Erol, Adnan Turani, and Nevide Gökaydın. She later completed her undergraduate education at the Department of Art Education, Buca Faculty of Education, Dokuz Eylül University. Between 1975 and 1980, she worked as a teacher and graphic designer at İzmir Buca Education Institute and also taught in the accelerated summer programs of Ankara Gazi Education Institute in 1975.

In 1995, Akdeniz was awarded the Painting Prize at the State Painting and Sculpture Exhibition. In her early works, a critical observation of İzmir’s urban life and its inhabitants predominates, occasionally incorporating ironic elements. In the 1990s, however, she turned toward a new mode of expression in which she interpreted details of nature through a photorealistic technique. These paintings are notable for their meticulous craftsmanship and a colorist approach dominated by shades of blue and green.

Having participated in group exhibitions at various museums and galleries in Berlin, Cologne, Paris, Düsseldorf, and London, Nadide Akdeniz continues to live and work in Istanbul.